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Lancet 373, 18741882

PMID: 63 RahdarAHajinezhadMRSargaziSBilalMBaraniMKarimiPet al

Histological examination of these plaques has revealed abnormal proliferation of keratinocytes, as well as immunocyte and vascular proliferation and infiltration [18]

Carnitine has been shown to be an endogenous substance with anti-inflammatory properties [47], as it inhibits the activity of NF-B and other core transcription factors involved in the inflammatory response and effectively reduces the levels of proinflammatory cytokines (e.g., IL-1, IL-6, and TNF-) [48, 49]

Through kinome-wide synthetic lethal RNAi screening combined with unbiased datamining of cell line platinum response in CCLE and GDSC databases, here we report that Src-Related Kinase Lacking C-Terminal Regulatory Tyrosine And N-Terminal Myristylation Sites (SRMS), a non-receptor tyrosine kinase, is a novel negative regulator of MKK4-JNK signaling under platinum treatment and plays an important role in dictating platinum efficacy in ovarian cancer

Shaved : Slice Brussels sprouts in half lengthwise