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Data from the Religious Orders Study/Memory and Ageing Project (ROS/MAP) cohort revealed that approximately 97% of persons diagnosed with probable AD had other concomitant neurodegenerative or vascular comorbidities, including microinfarcts or any of the vessel diseases that are also commonly present and contribute to cognitive impairment, whereas more than 86% of older persons without cognitive impairment had vascular, AD or other degenerative comorbidities in the brain

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