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28-d live-in, 55% exercise- and diet-induced energy deficit phase with (200 mg testosterone enanthate per week, Testosterone, n = 24) or without (Placebo, n = 26) exogenous testosterone

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The causes can be broadly categorised into exogenous (external) and endogenous (internal) factors, with the latter being of greater clinical significance

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Located in the South East of England, it has been supplying water for more than 130 years