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Moreover, IGF-1 can promote M2 microglial polarization via the inhibition of TLR4/NF-B signaling transduction and lead to the elevation of neuroprotection factors such as IL-10 and TGF- to attenuate microglia-mediated inflammation (Sun et al

In zebrafish models, the deletion of dnmt3 caused severe defects in the brain and retina, severely impairing normal neurogenesis

NMR Biomed 22(7):737744 de Kloet ER, Jols M, Holsboer F (2005) Stress and the brain: from adaptation to disease

For bodybuilders, the glucagon receptor activity is particularly compelling because it directly increases energy expenditure and preferentially targets visceral fat

Jin KW, Ro JW, Shin YJ, Hyon JY, Wee WR, Park SG

Cells were harvested by centrifugation at 7000 rpm in iterations of 10 min