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Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment

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Experimental investigations have extensively utilized GSH for studies of redox biology, thiol chemistry, enzyme-cofactor interactions, glutathione-dependent regulatory networks, and signal transduction mechanisms involving sulfur-containing biomolecules

Science 240, 16481652

doi: 10.3390/antiox9090901