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7A, qRT-PCR experiments were employed to assess the expression of inflammatory factors in CD4 + T cells

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Among them, the expression levels of FGF23, Klotho and CYP24A1 decreased, whereas the expression level of CYP27B1 increased, and the effect became more obvious with increasing Astragalus concentration

138 , 139 With further clarification of the links between metabolism and function of relevant Tcell subsets, it may become possible to modulate metabolic pathways to facilitate Tcell development and activation