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Importantly, pretreatment with 20 M NFT reduced the requirement for NFT after a washout phase to achieve the same intracellular glutathione levels (Fig

Psychiatry 55 : 165171 (2004)

The therapeutic potential of NAC has also been proposed to involve the modulation of glutamatergic neurotransmission in the brain [29]

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However, ongoing IV treatments can be costly and time-consuming, making them less practical for long-term use

Notably, glucose metabolic imbalance contributes to increase the oxidative stress, impairing ATP production, thus providing a hint for the exacerbation of neurodegeneration 25