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It also exerts neuroprotective effects by directly or indirectly inhibiting the gene expression of glycogen synthase kinase 3 (GSK3) [56, 57]

DUBs are involved in many different cellular pathways, such as controlling proteasome-mediated protein degradation 2,11,13 , DNA damage response 11,14,15,16 , and innate immune signaling 11,17 and are implicated to be involved in different diseases 18,19,20,21,22

10.1016/j.molcel.2011.06.028 Mol

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Gene-based genome-wide association analysis in European and Asian populations identified novel genes for rheumatoid arthritis

Electroacupuncture can inhibit ferroptosis and treat neuropathic pain by regulating the SAT1/ALOX15 pathway, providing a new therapeutic target for neuropathic pain