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The main pathological features of pathological scars include abnormal proliferation and apoptosis inhibition of fibroblasts, as well as imbalance of collagen metabolism, leading to excessive extracellular matrix (ECM) deposition

A study by Elgendy et al (92) indicated that glucose consumption and lactate production increased in a time- and dose-dependent manner after HCT116 cells were treated with metformin, indicating that the rates of glycolysis increased

All statistical analyses were conducted using the R software, for both data analysis and visualization

PMCID: PMC7598719

Ipamorelin signals the pituitary gland to release growth hormone, which can impact metabolism, tissue repair, sleep cycles, and overall energy levels