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In KRAS mutated colorectal cancer cells the pentose phosphate pathway has been demonstrated to be essential for the growth in aerobic conditions and glutamine conversion into -ketoglutarate and alanine aminotransferase for KRAS induced anchorage-independent growth (83)

Chen et al., developed glucose-modified quercetin liposomes (QU-Glu-Lip) to improve the poor solubility, bioavailability, and brain delivery of quercetin

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10,11 In clinical practice, many patients express concerns about pore visibility and seek effective treatments

While few pathogens can infect the placenta and fetus in humans, maternal infection doesnt guarantee placental or fetal infection ( Additionally, the placenta is a source of autocrine, paracrine, and endocrine factors

Therefore, we hypothesized that the excessive expression of GJs post-APAP exposure in hepsin / mice could be a key factor contributing to the increased severity of liver damage observed following APAP administration