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For more information, read this article which looks at the connection between thiamine deficiency and small intestinal bacterial overgrowth: When Sibo & Ibs-Constipation Are Just Unrecognized Thiamine Deficiency Thiamine also exerts direct effects on the intestinal barrier

For the IV regimen, a loading dose of 150 mg/kg in 200 cc is given for 15 minutes, followed by 50 mg/kg in 500 cc over 4 hours and then 100 mg/kg in 1000 cc over 16 hours

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He had Lyme disease and multiple co infections

Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14

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