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FA is caused by mutations in the frataxin gene ( FXN ), which results in a deficiency of the mitochondrial protein frataxin (FXN) [8]

Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy

Finally, in most forms of cell death, there is the accumulation of oxygen free radicals, mitochondrial dysfunction, et al

Antibodies were incubated using an automatic IHC staining instrument (Ventana, Tucson, AZ, USA) according to the manufacturers protocols

However, the extent to which NRF2 regulates its target genes beyond promoter-restricted regions, and the significance of this regulation to NRF2-dependent cancer cell maintenance, remains unexplored

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