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658 Similarly, AAV9-TAZ ameliorates mitochondrial structural defects in a Barth syndrome mouse model, improving cardiac and skeletal muscle function 659,660 and rescuing neonatal mice from mortality, cardiac dysfunction, and fibrosis

doi: 10.1016/j.fsi.2012.05.027

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Methotrexate-loaded nanoparticle DNA scavengers (cNP-pp-PEG) have been developed to directly reach the core of inflammation, which not only mitigate systemic toxicity possibly induced by the strong positive charge of cationic nanoparticles (cNPs) during intravenous circulation but also enhance the therapeutic effect of cNPs (93)