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doi: 10.3390/metabo12111059 18

Recent studies demonstrated that Notch signaling is required for the adhesion of VSMCs but not other types of VSMC-derived cells in the formation of the cap in mouse atherosclerosis, and reduction of Notch signaling is a prerequisite for medial VSMC mediating the development of plaque, 248 suggesting that sequential loss and gain of Notch signaling is required for the recruitment of cap SMC population in atherosclerosis

As an adult, 80% of your dermis is composed of collagen, which gives your skin its strength and prevents it from being torn when overstretched

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Inflammation is a key component and contributor in the pathophysiology of ischemia, existing in every stage of the ischemic cascade (Iadecola and Anrather, 2011)

10.1111/febs.14138 50 PerrotT.SchwartzM.SaiagF.SalzetG.DumarayS.FavierF.et al (2018)