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J Dent 2016;51:1520

At low doses, aspartame was a potential angiogenic agent that could induce regenerative cytokine production

10.1016/j.phymed.2019.153095 109 LiY.TranV

Laboratory tests revealed significantly elevated C-reactive protein (CRP) (61.33 mg/L) and white blood cell count (22.84 10/L)

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The main objective is to suppress menses, thus inducing iatrogenic menopause or pseudopregnancy, which in turn reduces pain symptoms in order to prevent or postpone surgery, which is useful for long-term management of the disease