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Al inhibir selectivamente la nicotinamida N-metiltransferasa (NNMT), el 5-amino-1MQ ayuda a preservar los niveles intracelulares de NAD+ y a redirigir el metabolismo energtico celular hacia una mayor oxidacin de grasas y eficiencia mitocondrial

Methylation Capacity Second, NNMT inhibition affects cellular methylation capacity: SAM is required for hundreds of methyltransferase reactions throughout the cell, and NNMT's consumption of SAM can deplete this critical resource, while the SAH produced by NNMT is a potent product inhibitor of many methyltransferases

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Human evidence is more limited and less definitive than for FDA approved anti obesity medications