ISBN 978-0323400046
This broad receptor engagement profile means that Melanotan II simultaneously activates melanogenic pathways (MC1R on melanocytes), appetite and energy homeostasis circuits (MC3R/MC4R in hypothalamus), and exocrine gland function pathways (MC5R), making it essential for researchers to design appropriate controls and selective antagonists into experimental protocols to attribute observed effects to specific receptor subtypes
Regarding the expression of mucin core proteins, vulvar Paget disease may arise from ectopic MUC5AC-positive cells originating from Bartholin or some other unidentified glands, while the unique expression of MUC2 in perianal Paget disease indicates that its origin from colorectal mucosa differs from that in the vulva
Product Specifications CAS Number: 75921-69-6 Peptide Sequence: AcSerTyrSerMetGluHisPheArgTrpGlyLysProValNH Molecular Formula: CHNO Molecular Weight: 874 g/mol Subcategory: Aesthetic & Cosmetic Peptides Synonyms: MT-1 Purity: 95% (verified by HPLC and mass spectrometry) Packaging Format: 10 mg lyophilized powder in sterile research vial Storage Conditions: Store at 28 C or frozen at 20 C as appropriate
[PUBMED Abstract] Leitao MM, Cheng X, Hamilton AL, et al.: Gynecologic Cancer InterGroup (GCIG) consensus review for vulvovaginal melanomas
Store in original sealed vials, protected from light
