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7a, 11b, 12a,c and 14a were created using BioRender ( Ethics declarations Competing interests J.M.M

Song TY, Lin HC, Chen CL et al (2014) Ergothioneine and melatonin attenuate oxidative stress and protect against learning and memory deficits in C57BL/6J mice treated with D-galactose

The membrane was blocked with 4% skim milk containing 0.1% tween-20 for 1 h

By integrating evidence from both preclinical and clinical studies, we evaluate the translational potential of metformins pleiotropic actions across specific cardiac pathologies and outline key directions for future research and therapeutic innovation

The LPS is a surface membrane component of gram-negative bacteria and is recognized by toll-like receptor 4 (TLR4) on the membranes of intestinal epithelial cells, which stimulates components of the immune system [67]

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