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ACT-based immunotherapies can elicit significant tumor regression in animal models and also up to 70% of metastatic melanoma patients

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Kaneko et al

The key histological abnormalities of AD include necrosis and apoptosis of VSMCs, fracture of elastic fibers, and degradation of extracellular matrix (ECM) (73).The thrombi formed within the false lumen indicates the presence of continued inflammation under the condition of atherosclerosis and chronic inflammation, and the higher risk of rupture in patients with inflammatory diseases demonstrates the importance of inflammation in AD (74)

Prognostic significance of baseline peripheral absolute neutrophil, monocyte and serum 2-microglobulin level in patients with diffuse large b-cell lymphoma: a new prognostic model