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This occurs through the regulation of NRF2, a nuclear factor responsible for modulating the expression of genes related to anti-inflammatory responses and cell survival in the vascular endothelium [62]

doi:10.1056/NEJMc2104974

CT scans which were done for all patients before starting the supplements and after showed that patients who took glutathione over 3 months had no new stone formation and the size of the already presented stones was still the same or reduced, while those patients who took placebo for the same period developed new stones and the size of already presented stones increased

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The underlying clinical question has not changed

Fanelli S, Francioso A, Cavallaro R, et al