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Front Endocrinol (Lausanne) 16:1576850

SREBP1, a primary transcriptional regulator of lipogenesis, is overexpressed in many cancer types

;12(12) McQuade RM, Carbone SE, Stojanovska V, Rahman A, Gwynne RM, Robinson AM et al (2016) Role of oxidative stress in oxaliplatin-induced enteric neuropathy and colonic dysmotility in mice

Upon exposure to DNA damage-inducing stimuli such as ionizing radiation, the RAD51 Cys319 site undergoes oxidation, allowing it to polymerize with PRDX1, thereby facilitating the formation of RAD51 foci

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Ferroptosis, a form of regulated cell death driven by iron accumulation and lipid peroxidation, has emerged from preclinical studies as a potentially important mechanism contributing to pulmonary fibrosis progression