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10.52547/rbmb.10.3.506 29 DesvergneB.MichalikL.WahliW

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Enterovirus as trigger of coeliac disease: nested case-control study within prospective birth cohort

Studies by Xu et al (44) demonstrated that TSA downregulates LOX-1 expression in macrophages (both the RAW 264.7 cell line and primary mouse peritoneal macrophages) by inhibiting the NF-B signaling pathway, thus reducing ox-LDL uptake and foam cell formation, and ultimately exerting anti-atherosclerotic effects

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This demonstrated that the hydroxyl groups can greatly increase the light-responsive catalytic activity of CDs, while the slight amount of carboxyl groups acts as an inhibitor of catalytic activity