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Metabolite levels are influenced by both genetic and environmental factors, providing a snapshot of the biochemical activity within cells and tissues

Basal Cells An important feature of epithelial cell remodeling in IPF is the expansion of distal basal cells, which can serve as stem/progenitor cells of the pseudostratified epithelium of the lung

Herfarth, H

It is worth noting that the derivation of HBGVs applies extrapolation factors (also termed safety factors) to account for toxicodynamic and toxicokinetic differences between species and inter-individual variability in humans

Results Intake of AGE-containing UPFs is positively correlated with allergic diseases As a considerable component of the modern and western diet, UPFs are recognized as a primary source of AGEs in the diet 14,15