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Nevertheless, previous vaccine studies for SARS-CoV suggest that vaccine-induced antibodies may directly promote enhanced disease upon exposure to the virus via the activation of macrophages able to produce high levels of the chemokine CCL2 and the cytokine IL-8, resulting in lung injury 5

During in vitro dissolution testing, the nanosuspension demonstrated a controlled release profile

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The only adverse event was one case of mild scalp itching in the active treatment group

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They are also high in fibre and have shown a beneficial impact on blood cholesterol levels