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Altogether, these data suggest that it is NADPH depletion associated with cysteine generation that causes SLC7A11-high cancer cell death under conditions of glucose starvation ( Figure 2 ) ( Figure 2 )

Crucially, besides inducing membrane depolarization through 7nAChR-gated Ca2+ conductance, there is growing evidence suggesting potential metabotropic activities of this ionotropic receptor [43]

Twenty-one days later, all mice were subjected to CCI injury

Measurement of GSH/GSSG level For GSH/GSSG level, 143B cells were plated in 12-well plates

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