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Figure 4: Time-course of the Change from Baseline in ADAS-cog Score for Patients Completing the 15-week Study

Lappano R, Santolla MF, Pupo M, et al

We also established that the LD 50 for ZnBG was 19.5 mol/kg BW, which is similar to an LD 50 of 23 mol/kg BW shown in earlier studies in rats (Vreman et al., 1991)

This avoids a more sudden rush of activity, which can cause irritation

S.JinH.et al (2019)

The data are shown as actual TF latencies (sec) and as maximum possible effect (%MPE) using the formula, %MPE = [(post-injection TF latency baseline TF latency)/(12 baseline TF latency)] 100