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While pure L-carnitine primarily targets the energy demands of the heart and skeletal muscles, other forms, such as Acetyl-L-carnitine (ALCAR), are specifically structured to cross the blood-brain barrier, providing targeted support for neurological function and cognitive stamina

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In Alzheimers disease, PHGDH upregulation, an upstream control point in the serine synthesis pathway, supports the idea that disrupted serine metabolism is coupled to persistent neuroinflammatory signaling 73

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