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Disease-a-month : DM

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Experiments in animals with uniformly labeled 13C-glutamine demonstrated that glutathione was enriched with five 13C atoms, indicating that glutamine is the primary source for glutathione synthesis [11]

therefore, targeting such pathways holds clinical promise, as exemplified by the development of bromodomain and extra-terminal (BET) inhibitors 2,3

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It binds presynaptically to the GABA-B receptors in the brain and spinal cord and is thought to decrease monosynaptic and polysynaptic reflexes