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Toxicity of DCVC to kidney cells has been associated with (1) covalent modification of macromolecules, (2) depletion of nonprotein thiols (presumably mostly GSH), (3) lipid peroxidation (Beuter et al., 1989, Chen et al., 1990, Groves et al., 1991), and (4) carbonylation of susceptible proteins (Fan et al., 2014)

Musculoskeletal/soft tissue: Arthralgia, arthritis (may represent reactivation in patients with quiescent rheumatoid arthritis - See PRECAUTIONS: General), myalgia

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10.3389/fphys.2023.1081186 165 MishraG.SinghP.GargV.ParvezN.YadavS.HwisaN.et al (2011)