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Down Regulation: the number of receptors decreases (by proteolysis) upon exposure to a high concentration of agonist for a very long time (hours), making the cell less responsive to the same agonist or others that work at the same receptor

Nevertheless, building upon the optimized system and potentially incorporating methods like monitoring cell membrane depolarization, there is prospective potential to adapt the technology for rapid AST of slow-growing microorganisms, thereby expanding its application scope

These come in 1000 g/mL vials (1 mg per mL)

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