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sativa ), commonly known as black cumin, has been extensively used in neurodegenerative diseases like Parkinsons and Alzheimers disease because of its antioxidant potential ( Nigella sativa improves the clinical manifestations of EAE reducing the relapse days, improving the daily body weight, increasing locomotor activity, decreasing anxiety, and reducing the neuronal damage in the deep cerebral cortex (Mohamed et al., 2005)

The mechanism underlying these cognitive improvements involves direct enhancement of synaptic connectivity

[9] revealed that the number of dengue cases reported worldwide in 2010 was approximately 390 million, of which 96 million represent apparent dengue infections (dengue haemorrhagic fever or dengue shock syndrome)

Pumpkin Seed & Saw Palmetto Both reduce DHT via sterol-mediated 5-AR inhibition (Cid-Arias et al., 2020)

Cadmium disrupted ER Ca(2+) homeostasis by inhibiting SERCA2 expression and activity to induce apoptosis in renal proximal tubular cells